Example — B. subtilis lipase A
Job 8d059543e3f1 · 212 aa ·
5 designs/phenotype · 1 phenotype(s)
pLDDT: 83.0
TM-score: 0.982
MPNN score: 1.23
Δ charge: -3
MKTAYIAKQRQISFVKSHFSRLLEERLGLIEVQAPILSRVGKGTQDNLSGAEKAVQVKEKALPDAQFEVVHSLAKWKRQTLGQHDDSAGEGLYTHMKALRPDEDRLSPLHSVYVDQMDWERVMGDIERQFSTLKSTVEAIWAGIKATEAAVSEEFG
Wild-type (amber) overlaid with design (magma). Active-site residues highlighted.
pLDDT: 78.4
TM-score: 0.954
MPNN score: 1.4
Δ charge: 1
MKTAYIAKQRQISFVKSHFSRQLEERLGLIEVQAPILSRVGDGTQDNLSGAEKAVQVKVKALPDAQFEVVHSLAKWKRQTLGQHDASAGEGLYTHMKALRPDEDRLSPLHSRTVDQWDWERVMGDGERQFSTLKSTVEAIWAGIKATEAAVSEEFG
Wild-type (amber) overlaid with design (magma). Active-site residues highlighted.
pLDDT: 81.6
TM-score: 0.982
MPNN score: 1.34
Δ charge: -1
MKTAYIAKQRQISFVKSHFSRQLEERLGLIEVQAPILSRVGDGTQTNLNGAEKAVQVKVKALPDAQFEVVHSLAKWKRQTLGQHDFSAGEGLYTHMCALRPDEDRLSPLHSVQVDQWDWERVMGDGERQFSTLKSTVEAIWAGIFATHAAVSEEFG
Wild-type (amber) overlaid with design (magma). Active-site residues highlighted.
pLDDT: 71.9
TM-score: 0.881
MPNN score: 1.17
Δ charge: 1
MKTAYIAKQRQISFVKSHFSRQLEERLGLIEVQAPILSRVGDGTQDNLSGAEKAVQVKSKALPDAQFEVVHSLAKWKRQTLGQHDFSAGQGLYTHMKALRPDEDRLSPLHSVYVDQWDWERVMGDGERQFSTLKSTVEAIWAGIKATEAAVSEEFG
Wild-type (amber) overlaid with design (magma). Active-site residues highlighted.
pLDDT: 80.7
TM-score: 0.883
MPNN score: 1.12
Δ charge: 3
MKTAYIAKQRQISFVKSHFSGQLEERLGLIEVQAEILSRVGDGTQDNLSGAEKAVQVKVKALPDAQFEVVHSLAKWKRQTLGQHDFSAGEVLYTHMKAIRPDEDRLSPLHSVYVDQWDWERVMGDGERQFSTLKETVEAIWAGIKATEAAVSEEFG
Wild-type (amber) overlaid with design (magma). Active-site residues highlighted.